The George-Huntington-Institute (GHI) located in Münster, Germany is devoted to clinical care and preclinical and clinical research in Huntington’s disease (HD). GHI entertains one of the largest HD out-patient clinics for symptomatic and premanifest gene carriers, persons at-risk and caregivers around the world. GHI offers participation in ENROLL-HD, HD-Clarity and multiple clinical trials aimed at improving therapeutic options for HD.