The Digital and Quantitative Medicine (DQM) group at Biogen is a multi-disciplinary group of physicians and scientists whose purpose is to provide Biogen with methods for the quantification of the health state of patients and provide a rigorous paradigm for improving clinical trial outcomes. DQM applies a physician-scientist model to incorporate multi-scale computational modelling and simulation to bring specific value to development and discovery, catalyzing the organization towards a human-centric transformative quantitative biology strategy for drug development/discovery. DQM includes platforms in clinical technologies (including digital and internet of things approaches), quantitative medicine and experimental medicine and relies on robust interfaces with groups across Biogen.